ncRNA name | hsa-miR-4430 |
ncRNA Category | miRNA |
Disease name | uveal melanoma (UM) |
Species | Homo sapiens |
Tissues/Cell_line | dog UM samples |
Methods | microarray |
Expression pattern | up-regulated |
Functional description | Ten of the miRNAs showed increased expression in the metastasizing tumours (with 6 showing >2-fold increase). Class prediction analysis pinpointed 9 miRNAs which categorized tumours as metastasizing or non-metastasizing with an accuracy of 89%. The expression of 4 of the miRNAs was subsequently measured using RT-qPCR, and their up-regulation in metastasizing tumours validated. |
PubMed ID | 28512868 |
Year | 2018 |
Title | Metastasis-associated microRNA expression in canine uveal melanoma. |
Drug-related ncRNA | NO |
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